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Comparative sequence analysis suggests a conserved gating mechanism for TRP channels

The transient receptor potential (TRP) channel superfamily plays a central role in transducing diverse sensory stimuli in eukaryotes. Although dissimilar in sequence and domain organization, all known TRP channels act as polymodal cellular sensors and form tetrameric assemblies similar to those of t...

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Detalles Bibliográficos
Autores principales: Palovcak, Eugene, Delemotte, Lucie, Klein, Michael L., Carnevale, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485022/
https://www.ncbi.nlm.nih.gov/pubmed/26078053
http://dx.doi.org/10.1085/jgp.201411329