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Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study

As little as a decade ago, generation of a single knockout mouse line was an expensive and time-consuming undertaking available to relatively few researchers. The International Knockout Mouse Consortium, established in 2007, has revolutionized the use of such models by creating an open-access reposi...

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Detalles Bibliográficos
Autores principales: Coleman, James L. J., Brennan, Karen, Ngo, Tony, Balaji, Poornima, Graham, Robert M., Smith, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485191/
https://www.ncbi.nlm.nih.gov/pubmed/26175717
http://dx.doi.org/10.3389/fendo.2015.00105