Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine

Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated trai...

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Detalles Bibliográficos
Autores principales: Yang, Can, Li, Cong, Wang, Qian, Chung, Dongjun, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485215/
https://www.ncbi.nlm.nih.gov/pubmed/26175753
http://dx.doi.org/10.3389/fgene.2015.00229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485215/
https://www.ncbi.nlm.nih.gov/pubmed/26175753
http://dx.doi.org/10.3389/fgene.2015.00229

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