Clostridial C3 Toxins Target Monocytes/Macrophages and Modulate Their Functions

The C3 enzymes from Clostridium (C.) botulinum (C3bot) and Clostridium limosum (C3lim) are single chain protein toxins of about 25 kDa that mono-ADP-ribosylate Rho-A, -B, and -C in the cytosol of mammalian cells. We discovered that both C3 proteins are selectively internalized into the cytosol of mo...

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Detalles Bibliográficos
Autores principales: Barth, Holger, Fischer, Stephan, Möglich, Amelie, Förtsch, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485225/
https://www.ncbi.nlm.nih.gov/pubmed/26175735
http://dx.doi.org/10.3389/fimmu.2015.00339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485225/
https://www.ncbi.nlm.nih.gov/pubmed/26175735
http://dx.doi.org/10.3389/fimmu.2015.00339

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