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A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome

Currently, very few prognosticators accurately predict metastasis in cancer patients. In order to complete the metastatic cascade and successfully colonize distant sites, carcinoma cells undergo dynamic epithelial-mesenchymal-transition (EMT) and its reversal, mesenchymal-epithelial-transition (MET)...

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Detalles Bibliográficos
Autores principales: Soundararajan, Rama, Paranjape, Anurag N., Barsan, Valentin, Chang, Jeffrey T., Mani, Sendurai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485318/
https://www.ncbi.nlm.nih.gov/pubmed/26123483
http://dx.doi.org/10.1038/srep11766