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Cytoplasmic nucleophosmin has elevated T199 phosphorylation upon which G2/M phase progression is dependent
The cytoplasmic mutant of nucleophosmin (NPMc) is found approximately in one-third of acute myeloid leukemia (AML) cases and is highly associated with normal karyotype. Whereas previous studies have focused on wtNPM in centrosome duplication, we further elucidate the role of NPM in the cell cycle by...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485321/ https://www.ncbi.nlm.nih.gov/pubmed/26123729 http://dx.doi.org/10.1038/srep11777 |