The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

BACKGROUND: The peroxisome proliferator-activated receptor alpha (PPARα) controls lipid/energy homeostasis and inflammatory responses. The truncated splice variant PPARα-tr was suggested to exert a dominant negative function despite being unable to bind consensus PPARα DNA response elements. METHODS...

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Detalles Bibliográficos
Autores principales: Thomas, Maria, Bayha, Christine, Klein, Kathrin, Müller, Simon, Weiss, Thomas S., Schwab, Matthias, Zanger, Ulrich M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485637/
https://www.ncbi.nlm.nih.gov/pubmed/26122096
http://dx.doi.org/10.1186/s12885-015-1500-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485637/
https://www.ncbi.nlm.nih.gov/pubmed/26122096
http://dx.doi.org/10.1186/s12885-015-1500-x

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