Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

Angiosarcoma (AS) is a rare neoplasm of endothelial origin that has limited treatment options and poor five-year survival. Using tumorgraft models, we previously showed that AS is sensitive to small-molecule inhibitors that target mitogen-activated/extracellular-signal-regulated protein kinase kinas...

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Detalles Bibliográficos
Autores principales: ANDERSEN, NICHOLAS J., BOGUSLAWSKI, ELISSA B., KUK, CYNTHIA Y., CHAMBERS, CHRISTOPHER M., DUESBERY, NICHOLAS S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485647/
https://www.ncbi.nlm.nih.gov/pubmed/25955301
http://dx.doi.org/10.3892/ijo.2015.2989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485647/
https://www.ncbi.nlm.nih.gov/pubmed/25955301
http://dx.doi.org/10.3892/ijo.2015.2989

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