Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability

Poor water solubility of a drug is a major challenge in drug delivery research and a main cause for limited bioavailability and pharmacokinetic parameters. This work aims to utilize custom fractional factorial design to assess the development of self-nanoemulsifying drug delivery systems (SNEDDS) an...

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Detalles Bibliográficos
Autores principales: Hashem, Fahima M, Al-Sawahli, Majid M, Nasr, Mohamed, Ahmed, Osama AA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485649/
https://www.ncbi.nlm.nih.gov/pubmed/26150693
http://dx.doi.org/10.2147/DDDT.S86126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485649/
https://www.ncbi.nlm.nih.gov/pubmed/26150693
http://dx.doi.org/10.2147/DDDT.S86126

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