Direct and indirect targeting of MYC to treat acute myeloid leukemia

PURPOSE: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and is often resistant to conventional therapies. The MYC oncogene is commonly overexpressed in AML but has remained an elusive target. We aimed to examine the consequences of targeting MYC both directly and indirectly...

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Detalles Bibliográficos
Autores principales: Brondfield, Sam, Umesh, Sushma, Corella, Alexandra, Zuber, Johannes, Rappaport, Amy R., Gaillard, Coline, Lowe, Scott W., Goga, Andrei, Kogan, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485702/
https://www.ncbi.nlm.nih.gov/pubmed/25956709
http://dx.doi.org/10.1007/s00280-015-2766-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485702/
https://www.ncbi.nlm.nih.gov/pubmed/25956709
http://dx.doi.org/10.1007/s00280-015-2766-z

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