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Modulating gut immunity and neoplasia with oral cytokine adjuvants
Oral administration of particulate IL-10 suppressed polyposis, ameliorated systemic pathology and extended lifespan in APC(min/+) mice. Therapeutic effect was associated with selective activity of IL-10 on intestinal CD4+Foxp3+RORγt+IL-17+ pathogenic T-regulatory cells. Studies were recently extende...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485710/ https://www.ncbi.nlm.nih.gov/pubmed/26137401 http://dx.doi.org/10.1080/2162402X.2014.1002724 |