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Immune independent crosstalk between lymphoma and myeloid suppressor CD14(+)HLA-DR(low/neg) monocytes mediates chemotherapy resistance

We have previously reported a novel phenotype of myeloid suppressors in lymphoma patients characterized by a loss of HLA-DR expression on monocytes, CD14(+)HLA-DR(low/neg). These cells were directly immunosuppressive and were associated with poor clinical outcome. In this study, we found that lympho...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe (Jenny), Bulur, Peggy A, Dogan, Ahmet, Gastineau, Dennis A, Dietz, Allan B, Lin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485750/
https://www.ncbi.nlm.nih.gov/pubmed/26137410
http://dx.doi.org/10.1080/2162402X.2014.996470