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Restoration of natural killer activity in hepatocellular carcinoma by treatment with antibody against granulin-epithelin precursor

Impairment of natural killer (NK) cell activity is an important mechanism of tumor immunoevasion. We have previously shown that expression of granulin-epithelin precursor (GEP) in hepatocellular carcinoma (HCC) cells rendered the cells resistant to NK cell immunosurveillance. Here, we examined wheth...

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Detalles Bibliográficos
Autores principales: Cheung, Phyllis FY, Yip, Chi Wai, Ng, Linda WC, Wong, Chun Kwok, Cheung, Tan To, Lo, Chung Mau, Fan, Sheung Tat, Cheung, Siu Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485783/
https://www.ncbi.nlm.nih.gov/pubmed/26140244
http://dx.doi.org/10.1080/2162402X.2015.1016706