Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation

Stimulating the immune system to attack cancer is a promising approach, even for the control of advanced cancers. Several cytokines that promote interferon-γ-dominated immune responses show antitumor activity, with interleukin 12 (IL-12) being of major importance. Here, we used an antibody-IL-12 fus...

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Detalles Bibliográficos
Autores principales: Schilbach, Karin, Alkhaled, Mohammed, Welker, Christian, Eckert, Franziska, Blank, Gregor, Ziegler, Hendrik, Sterk, Marco, Müller, Friederike, Sonntag, Katja, Wieder, Thomas, Braumüller, Heidi, Schmitt, Julia, Eyrich, Matthias, Schleicher, Sabine, Seitz, Christian, Erbacher, Annika, Pichler, Bernd J, Müller, Hartmut, Tighe, Robert, Lim, Annick, Gillies, Stephen D, Strittmatter, Wolfgang, Röcken, Martin, Handgretinger, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485786/
https://www.ncbi.nlm.nih.gov/pubmed/26140238
http://dx.doi.org/10.1080/2162402X.2015.1014760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485786/
https://www.ncbi.nlm.nih.gov/pubmed/26140238
http://dx.doi.org/10.1080/2162402X.2015.1014760

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