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Shaping the tumor microenvironment with Modified Vaccinia Virus Ankara and TLR9 ligand

Our preclinical data demonstrate that an intravenous injection of Modified Vaccinia virus Ankara induces CD8(+) lymphocytes to infiltrate organs to control the growth of orthotopic renal carcinoma upon combination with a toll-like receptor 9 agonist. Such shaping of the tumor microenvironment could...

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Detalles Bibliográficos
Autores principales: Préville, Xavier, Rittner, Karola, Fend, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485804/
https://www.ncbi.nlm.nih.gov/pubmed/26155396
http://dx.doi.org/10.1080/2162402X.2014.1003013