Cargando…

Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8(+) T-cell responses and immune memory

Cancer chemotherapy using cytotoxic drugs can induce immunogenic tumor cell death; however, dosing regimens and schedules that enable single-agent chemotherapy to induce adaptive immune-dependent ablation of large, established tumors with activation of long-term immune memory have not been identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Junjie, Waxman, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485826/
https://www.ncbi.nlm.nih.gov/pubmed/26137402
http://dx.doi.org/10.1080/2162402X.2015.1005521