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Anticancer drug sensitivity prediction in cell lines from baseline gene expression through recursive feature selection

BACKGROUND: An enduring challenge in personalized medicine is to select right drug for individual patients. Testing drugs on patients in large clinical trials is one way to assess their efficacy and toxicity, but it is impractical to test hundreds of drugs currently under development. Therefore the...

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Detalles Bibliográficos
Autores principales: Dong, Zuoli, Zhang, Naiqian, Li, Chun, Wang, Haiyun, Fang, Yun, Wang, Jun, Zheng, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485860/
https://www.ncbi.nlm.nih.gov/pubmed/26121976
http://dx.doi.org/10.1186/s12885-015-1492-6