Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

Human NUDT16 is a member of the NUDIX hydrolase superfamily. After having been initially described as an mRNA decapping enzyme, recent studies conferred it a role as an “housecleaning” enzyme specialized in the removal of hazardous (deoxy)inosine diphosphate from the nucleotide pool. Here we present...

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Detalles Bibliográficos
Autores principales: Trésaugues, Lionel, Lundbäck, Thomas, Welin, Martin, Flodin, Susanne, Nyman, Tomas, Silvander, Camilla, Gräslund, Susanne, Nordlund, Pär
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485890/
https://www.ncbi.nlm.nih.gov/pubmed/26121039
http://dx.doi.org/10.1371/journal.pone.0131507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485890/
https://www.ncbi.nlm.nih.gov/pubmed/26121039
http://dx.doi.org/10.1371/journal.pone.0131507

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