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Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

Slowly inactivating Na(+) channels conducting “late” Na(+) current (I(Na,late)) contribute to ventricular arrhythmogenesis under pathological conditions. I(Na,late) was also reported to play a role in chronic atrial fibrillation (AF). The objective of this study was to investigate I(Na,late) in huma...

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Detalles Bibliográficos
Autores principales: Poulet, Claire, Wettwer, Erich, Grunnet, Morten, Jespersen, Thomas, Fabritz, Larissa, Matschke, Klaus, Knaut, Michael, Ravens, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485891/
https://www.ncbi.nlm.nih.gov/pubmed/26121051
http://dx.doi.org/10.1371/journal.pone.0131432