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Enhancing Interferon Regulatory Factor 7 Mediated Antiviral Responses and Decreasing Nuclear Factor Kappa B Expression Limit HIV-1 Replication in Cervical Tissues

Establishment of a productive HIV-1 infection in the female reproductive tract likely depends on the balance between anti-viral and pro-inflammatory responses leading to activation and proliferation of HIV target cells. Immune modulators that boost anti-viral and depress pro-inflammatory immune resp...

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Detalles Bibliográficos
Autores principales: Rollenhage, Christiane, Macura, Sherrill L., Lathrop, Melissa J., Mackenzie, Todd A., Doncel, Gustavo F., Asin, Susana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485897/
https://www.ncbi.nlm.nih.gov/pubmed/26121689
http://dx.doi.org/10.1371/journal.pone.0131919