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Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells

DCs express intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication. Thus, DCs are productively infected only at very low levels with HIV-1, and this non-permissiveness of DCs is suggested to go along with viral evasion. We now illustrate that complement-opsonized HIV-1 (HIV-...

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Detalles Bibliográficos
Autores principales: Posch, Wilfried, Steger, Marion, Knackmuss, Ulla, Blatzer, Michael, Baldauf, Hanna-Mari, Doppler, Wolfgang, White, Tommy E., Hörtnagl, Paul, Diaz-Griffero, Felipe, Lass-Flörl, Cornelia, Hackl, Hubert, Moris, Arnaud, Keppler, Oliver T., Wilflingseder, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485899/
https://www.ncbi.nlm.nih.gov/pubmed/26121641
http://dx.doi.org/10.1371/journal.ppat.1005005