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The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia. The pathological hallmarks of AD are amyloid plaques [aggregates of amyloid-beta (Aβ)] and neurofibrillary tangles (aggregates of tau). Growing evidence suggests that tau accumulation is pathologically more relevant to the developmen...

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Detalles Bibliográficos
Autores principales: Liu, Zhenzhen, Li, Tao, Li, Ping, Wei, Nannan, Zhao, Zhiquan, Liang, Huimin, Ji, Xinying, Chen, Wenwu, Xue, Mengzhou, Wei, Jianshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485995/
https://www.ncbi.nlm.nih.gov/pubmed/26171115
http://dx.doi.org/10.1155/2015/352723