Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD

An evolutionarily conserved unfolded protein response (UPR) component, IRE1, cleaves XBP1/HAC1 introns in order to generate spliced mRNAs that are translated into potent transcription factors. IRE1 also cleaves endoplasmic-reticulum-associated RNAs leading to their decay, an activity termed regulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Tam, Arvin B., Koong, Albert C., Niwa, Maho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486022/
https://www.ncbi.nlm.nih.gov/pubmed/25437541
http://dx.doi.org/10.1016/j.celrep.2014.09.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486022/
https://www.ncbi.nlm.nih.gov/pubmed/25437541
http://dx.doi.org/10.1016/j.celrep.2014.09.016

Ejemplares similares