Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis

Cancer cells often gains a growth advantage by taking up glucose at a high rate and undergoing aerobic glycolysis through intrinsic cellular factors that reprogram glucose metabolism. Focal adhesion kinase (FAK), a key transmitter of growth factor and anchorage stimulation, is aberrantly overexpress...

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Detalles Bibliográficos
Autores principales: Zhang, Jianliang, Gao, Qile, Zhou, Ying, Dier, Usawadee, Hempel, Nadine, Hochwald, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486081/
https://www.ncbi.nlm.nih.gov/pubmed/26119934
http://dx.doi.org/10.1038/onc.2015.256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486081/
https://www.ncbi.nlm.nih.gov/pubmed/26119934
http://dx.doi.org/10.1038/onc.2015.256

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