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Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS

BACKGROUND: Type I interferons (IFN-Is) serve as mediators of antiviral innate immunity and also regulate adaptive immune responses. The molecular mechanism that regulates virus-induced IFN-I production, particularly in tissue-resident immune cells, is incompletely understood. RESULTS: Here we ident...

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Detalles Bibliográficos
Autores principales: Xiao, Yichuan, Jin, Jin, Zou, Qiang, Hu, Hongbo, Cheng, Xuhong, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486122/
https://www.ncbi.nlm.nih.gov/pubmed/26131354
http://dx.doi.org/10.1186/s13578-015-0024-z