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Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS
BACKGROUND: Type I interferons (IFN-Is) serve as mediators of antiviral innate immunity and also regulate adaptive immune responses. The molecular mechanism that regulates virus-induced IFN-I production, particularly in tissue-resident immune cells, is incompletely understood. RESULTS: Here we ident...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486122/ https://www.ncbi.nlm.nih.gov/pubmed/26131354 http://dx.doi.org/10.1186/s13578-015-0024-z |