Construction and applications of exon-trapping gene-targeting vectors with a novel strategy for negative selection

BACKGROUND: Targeted gene modification by homologous recombination provides a powerful tool for studying gene function in cells and animals. In higher eukaryotes, non-homologous integration of targeting vectors occurs several orders of magnitude more frequently than does targeted integration, making...

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Detalles Bibliográficos
Autores principales: Saito, Shinta, Ura, Kiyoe, Kodama, Miho, Adachi, Noritaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486125/
https://www.ncbi.nlm.nih.gov/pubmed/26123730
http://dx.doi.org/10.1186/s13104-015-1241-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486125/
https://www.ncbi.nlm.nih.gov/pubmed/26123730
http://dx.doi.org/10.1186/s13104-015-1241-6

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