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Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22)

BACKGROUND: RUNX1/AML1, which is a Runt family transcription factor critical for normal hematopoiesis, is frequently mutated or translocated in a broad spectrum of hematopoietic malignancies. FINDINGS: We describe here the case of a 54-year-old female developed acute myeloid leukemia with a t(5;21)(...

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Detalles Bibliográficos
Autores principales: Yao, Hong, Pan, Jinlan, Wu, Chunxiao, Shen, Hongjie, Xie, Jundan, Wang, Qinrong, Wen, Lijun, Wang, Qian, Ma, Liang, Wu, Lili, Ping, Nana, Zhao, Yun, Sun, Aining, Chen, Suning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486139/
https://www.ncbi.nlm.nih.gov/pubmed/25879624
http://dx.doi.org/10.1186/s12943-015-0353-x