Endothelial CXCR7 Regulates Breast Cancer Metastasis

Atypical chemokine receptor CXCR7 (ACKR3) functions as a scavenger receptor for chemokine CXCL12, a molecule that promotes multiple steps in tumor growth and metastasis in breast cancer and multiple other malignancies. While normal vascular endothelium expresses low levels of CXCR7, marked upregulat...

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Detalles Bibliográficos
Autores principales: Stacer, Amanda C., Fenner, Joseph, Cavnar, Stephen P., Xiao, Annie, Zhao, Shuang, Chang, S. Laura, Salomonnson, Anna, Luker, Kathryn E., Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486335/
https://www.ncbi.nlm.nih.gov/pubmed/26119946
http://dx.doi.org/10.1038/onc.2015.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486335/
https://www.ncbi.nlm.nih.gov/pubmed/26119946
http://dx.doi.org/10.1038/onc.2015.236

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