Cargando…

Endothelial CXCR7 Regulates Breast Cancer Metastasis

Atypical chemokine receptor CXCR7 (ACKR3) functions as a scavenger receptor for chemokine CXCL12, a molecule that promotes multiple steps in tumor growth and metastasis in breast cancer and multiple other malignancies. While normal vascular endothelium expresses low levels of CXCR7, marked upregulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stacer, Amanda C., Fenner, Joseph, Cavnar, Stephen P., Xiao, Annie, Zhao, Shuang, Chang, S. Laura, Salomonnson, Anna, Luker, Kathryn E., Luker, Gary D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486335/ https://www.ncbi.nlm.nih.gov/pubmed/26119946 http://dx.doi.org/10.1038/onc.2015.236

Ejemplares similares

Imaging CXCL12-CXCR4 Signaling in Ovarian Cancer Therapy
por: Salomonnson, Emma, et al.
Publicado: (2013)

CXCL12-γ in Primary Tumors Drives Breast Cancer Metastasis
por: Ray, Paramita, et al.
Publicado: (2014)

Macroscopic Stiffness of Breast Tumors Predicts Metastasis
por: Fenner, Joseph, et al.
Publicado: (2014)

Scavenging of CXCL12 by CXCR7 Promotes Tumor Growth and Metastasis of CXCR4-positive Breast Cancer Cells
por: Luker, Kathryn E., et al.
Publicado: (2012)

CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7
por: Coggins, Nathaniel L., et al.
Publicado: (2014)

Constitutive and Chemokine-dependent Internalization and Recycling of CXCR7 in Breast Cancer Cells to Degrade Chemokine Ligands
por: Luker, Kathryn E., et al.
Publicado: (2010)

The CXCL12/CXCR4/ACKR3 Signaling Axis Regulates PKM2 and Glycolysis
por: Luker, Kathryn E., et al.
Publicado: (2022)

Correction: Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis
por: Chang, S. Laura, et al.
Publicado: (2017)

The CXCL12/CXCR7 signaling axis, isoforms, circadian rhythms, and tumor cellular composition dictate gradients in tissue
por: Spinosa, Phillip C., et al.
Publicado: (2017)

Imaging Sensitivity of Quiescent Cancer Cells to Metabolic Perturbations in Bone Marrow Spheroids
por: Cavnar, Stephen P., et al.
Publicado: (2016)

Microfluidic Endothelium for Studying the Intravascular Adhesion of Metastatic Breast Cancer Cells
por: Song, Jonathan W., et al.
Publicado: (2009)

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system
por: Sarma, Parishmita, et al.
Publicado: (2023)

Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis
por: Chang, S. Laura, et al.
Publicado: (2015)

Modeling Selective Elimination of Quiescent Cancer Cells from Bone Marrow
por: Cavnar, Stephen P., et al.
Publicado: (2015)

Fluorescence Lifetime Imaging of Apoptosis
por: Xiao, Annie, et al.
Publicado: (2015)

Short-Term Environmental Conditioning Enhances Tumorigenic Potential of Triple-Negative Breast Cancer Cells
por: Eckley, Samantha S., et al.
Publicado: (2019)

A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer(1,2)()()
por: Zhao, Shuang, et al.
Publicado: (2014)

A Caspase-3 Reporter for Fluorescence Lifetime Imaging of Single-Cell Apoptosis
por: Buschhaus, Johanna M., et al.
Publicado: (2018)

Three-dimensional tumor model mimics stromal – breast cancer cells signaling
por: Ham, Stephanie Lemmo, et al.
Publicado: (2017)

Oscillatory ERK Signaling and Morphology Determine Heterogeneity of Breast Cancer Cell Chemotaxis via MEK-ERK and p38-MAPK Signaling Pathways
por: Ho, Kenneth K. Y., et al.
Publicado: (2023)

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
por: Hernandez, Lorena, et al.
Publicado: (2011)

Murine alveolar macrophages limit replication of vaccinia virus
por: Rivera, Rachel, et al.
Publicado: (2007)

Protective Effect of Toll-like Receptor 4 in Pulmonary Vaccinia Infection
por: Hutchens, Martha A., et al.
Publicado: (2008)

Comparative study reveals better far-red fluorescent protein for whole body imaging
por: Luker, K.E., et al.
Publicado: (2015)

The dynamic yin-yang interaction of CXCR4 and CXCR7 in breast cancer metastasis
por: Hawkins, Oriana E, et al.
Publicado: (2012)

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity
por: Cruz-Orengo, Lillian, et al.
Publicado: (2011)

Targeting Disseminated Estrogen-Receptor-Positive Breast Cancer Cells in Bone Marrow
por: Buschhaus, Johanna M., et al.
Publicado: (2020)

Enhanced Bone Metastases in Skeletally Immature Mice
por: Haley, Henry R., et al.
Publicado: (2018)

In Vivo Imaging of Ligand Receptor Binding with Gaussia Luciferase Complementation
por: Luker, Kathryn E., et al.
Publicado: (2011)

Cancer-associated fibroblasts: challenges and opportunities
por: Tavana, Hossein, et al.
Publicado: (2023)

CXCR7 regulates breast tumor metastasis and angiogenesis in vivo and in vitro
por: Qian, Tingting, et al.
Publicado: (2018)

Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer
por: Humphries, Brock A., et al.
Publicado: (2020)

The effect of mechanosensitive channel MscL expression in cancer cells on 3D confined migration
por: Heureaux-Torres, Johanna, et al.
Publicado: (2018)

GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells
por: Inaguma, Shingo, et al.
Publicado: (2015)

Transitioning to a New Normal after COVID-19: Preparing to Get Back on Track for Cancer Imaging
por: Luker, Gary D., et al.
Publicado: (2020)

Impact of COVID-19 on Clinical Care and Research in Cancer Imaging: Where We Are Now
por: Luker, Gary. D, et al.
Publicado: (2021)

Cyclical Treatment of Colorectal Tumor Spheroids Induces Resistance to MEK Inhibitors
por: Shahi Thakuri, Pradip, et al.
Publicado: (2018)

Adapting Scientific Conferences to the Realities Imposed by COVID-19
por: Kalia, Vivek, et al.
Publicado: (2020)

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells
por: Lamichhane, Astha, et al.
Publicado: (2023)

Transition to the workplace
por: McColl, E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lj8qk9akj703or1t6hemuriugf