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Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis
OBJECTIVE: CD44E is a frequently overexpressed variant of CD44 in gastric cancer. Mechanisms that regulate CD44 splicing and expression in gastric cancer remain unknown. Herein, we investigated the role of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr 32000) in promoting tumor growth thro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486340/ https://www.ncbi.nlm.nih.gov/pubmed/26119931 http://dx.doi.org/10.1038/onc.2015.250 |