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Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension
Genome-wide association studies (GWAS) have prioritized a transcription factor, Nuclear Receptor 2 Family 2 (NR2F2), as being associated with essential hypertension in humans. Here we provide evidence that validates this association and indicates that Nr2f2 is a genetic determinant of blood pressure...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486351/ https://www.ncbi.nlm.nih.gov/pubmed/25687237 http://dx.doi.org/10.1038/ncomms7252 |