Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension

Genome-wide association studies (GWAS) have prioritized a transcription factor, Nuclear Receptor 2 Family 2 (NR2F2), as being associated with essential hypertension in humans. Here we provide evidence that validates this association and indicates that Nr2f2 is a genetic determinant of blood pressure...

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Detalles Bibliográficos
Autores principales: Kumarasamy, Sivarajan, Waghulde, Harshal, Gopalakrishnan, Kathirvel, Mell, Blair, Morgan, Eric, Joe, Bina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486351/
https://www.ncbi.nlm.nih.gov/pubmed/25687237
http://dx.doi.org/10.1038/ncomms7252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486351/
https://www.ncbi.nlm.nih.gov/pubmed/25687237
http://dx.doi.org/10.1038/ncomms7252

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