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Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans

BACKGROUND/OBJECTIVES: Obesity has been associated with both changes in adipose tissue lipid metabolism and inflammation. A key class of lipid-derived signalling molecules involved in inflammation are the prostaglandins. In this study, we aimed to determine how obesity affects the levels of prostagl...

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Detalles Bibliográficos
Autores principales: Virtue, S, Masoodi, M, de Weijer, B A M, van Eijk, M, Mok, C Y L, Eiden, M, Dale, M, Pirraco, A, Serlie, M J, Griffin, J L, Vidal-Puig, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486370/
https://www.ncbi.nlm.nih.gov/pubmed/25801691
http://dx.doi.org/10.1038/ijo.2015.34