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Models in biology: lessons from modeling regulation of the eukaryotic cell cycle
In this essay we illustrate some general principles of mathematical modeling in biology by our experiences in studying the molecular regulatory network underlying eukaryotic cell division. We discuss how and why the models moved from simple, parsimonious cartoons to more complex, detailed mechanisms...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486427/ https://www.ncbi.nlm.nih.gov/pubmed/26129844 http://dx.doi.org/10.1186/s12915-015-0158-9 |