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Leishmania is not prone to develop resistance to tamoxifen

Tamoxifen, an antineoplastic agent, is active in vitro and in vivo against the parasitic protozoa Leishmania. As part of our efforts to unravel this drug's mechanisms of action against the parasite and understand how resistance could arise, we tried to select tamoxifen-resistant Leishmania amaz...

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Detalles Bibliográficos
Autores principales: Coelho, Adriano C., Trinconi, Cristiana T., Senra, Luisa, Yokoyama-Yasunaka, Jenicer K.U., Uliana, Silvia R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486464/
https://www.ncbi.nlm.nih.gov/pubmed/26150922
http://dx.doi.org/10.1016/j.ijpddr.2015.05.006