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Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment()
Polo-like kinases (Plks) are a family of serine-threonine kinases that regulate multiple intracellular processes including DNA replication, mitosis, and stress response. Plk1, the most well understood family member, regulates numerous stages of mitosis and is overexpressed in many cancers. Plk inhib...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486469/ https://www.ncbi.nlm.nih.gov/pubmed/26055176 http://dx.doi.org/10.1016/j.tranon.2015.03.010 |