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Nicotinic receptors in non-human primates: analysis of genetic and functional conservation with humans
Nicotinic acetylcholine receptors (nAChRs) are highly conserved between humans and non-human primates. Conservation exists at the level of genomic structure, protein structure and epigenetics. Overall homology of nAChRs at the protein level is 98% in macaques versus 89% in mice, which is highly rele...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486519/ https://www.ncbi.nlm.nih.gov/pubmed/25661700 http://dx.doi.org/10.1016/j.neuropharm.2015.01.023 |