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Nicotinic receptors in non-human primates: analysis of genetic and functional conservation with humans

Nicotinic acetylcholine receptors (nAChRs) are highly conserved between humans and non-human primates. Conservation exists at the level of genomic structure, protein structure and epigenetics. Overall homology of nAChRs at the protein level is 98% in macaques versus 89% in mice, which is highly rele...

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Detalles Bibliográficos
Autores principales: Shorey-Kendrick, Lyndsey E., Ford, Matthew M., Allen, Daicia C., Kuryatov, Alexander, Lindstrom, Jon, Wilhelm, Larry, Grant, Kathleen A., Spindel, Eliot R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486519/
https://www.ncbi.nlm.nih.gov/pubmed/25661700
http://dx.doi.org/10.1016/j.neuropharm.2015.01.023