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NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma

A pivotal strategy to improve NK cell-mediated antitumor activity involves the upregulation of activating ligands on tumor cells. Enhancement of NK cell-mediated recognition of multiple myeloma cells was reported by us and others showing increased surface expression of NKG2D and DNAM-1 ligands on tu...

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Detalles Bibliográficos
Autores principales: Fionda, Cinzia, Soriani, Alessandra, Zingoni, Alessandra, Santoni, Angela, Cippitelli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486747/
https://www.ncbi.nlm.nih.gov/pubmed/26161387
http://dx.doi.org/10.1155/2015/178698