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Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway

Background. Activation of the adenosine A(2B) receptor (A(2B)R) can reduce myocardial ischemia/reperfusion (IR) injury. However, the mechanism underlying the A(2B)R-mediated cardioprotection is less clear. The present study was designed to investigate the potential mechanisms of cardioprotection med...

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Detalles Bibliográficos
Autores principales: Tian, Yikui, Piras, Bryan A., Kron, Irving L., French, Brent A., Yang, Zequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486757/
https://www.ncbi.nlm.nih.gov/pubmed/26161239
http://dx.doi.org/10.1155/2015/585297