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The Role of Dendritic Cells in Central Tolerance

Dendritic cells (DCs) play a significant role in establishing self-tolerance through their ability to present self-antigens to developing T cells in the thymus. DCs are predominantly localized in the medullary region of thymus and present a broad range of self-antigens, which include tissue-restrict...

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Detalles Bibliográficos
Autores principales: Oh, Jaehak, Shin, Jeoung-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486773/
https://www.ncbi.nlm.nih.gov/pubmed/26140042
http://dx.doi.org/10.4110/in.2015.15.3.111