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Neuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness and muscle atrophy related to the loss of upper and lower motor neurons (MNs) without a curative treatment. There is experimental evidence suggesting that retinoids may be involved in ALS pathoge...

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Detalles Bibliográficos
Autores principales: Riancho, Javier, Ruiz-Soto, María, Berciano, María T., Berciano, José, Lafarga, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486838/
https://www.ncbi.nlm.nih.gov/pubmed/26190974
http://dx.doi.org/10.3389/fncel.2015.00250