Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model

Muscle mass wasting is one of the most debilitating symptoms of myotonic dystrophy type 1 (DM1) disease, ultimately leading to immobility, respiratory defects, dysarthria, dysphagia and death in advanced stages of the disease. In order to study the molecular mechanisms leading to the degenerative lo...

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Detalles Bibliográficos
Autores principales: Bargiela, Ariadna, Cerro-Herreros, Estefanía, Fernandez-Costa, Juan M., Vilchez, Juan J., Llamusi, Beatriz, Artero, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486854/
https://www.ncbi.nlm.nih.gov/pubmed/26092529
http://dx.doi.org/10.1242/dmm.018127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486854/
https://www.ncbi.nlm.nih.gov/pubmed/26092529
http://dx.doi.org/10.1242/dmm.018127

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