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Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages

Acute schistosomiasis is characterized by pro-inflammatory responses against tissue- or organ-trapped parasite eggs along with granuloma formation. Here, we describe studies in Cx3cr1(−/−) mice and demonstrate the role of Cx3cr1 in the pathoetiology of granuloma formation during acute schistosomiasi...

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Detalles Bibliográficos
Autores principales: Ran, Lin, Yu, Qilin, Zhang, Shu, Xiong, Fei, Cheng, Jia, Yang, Ping, Xu, Jun-Fa, Nie, Hao, Zhong, Qin, Yang, Xueli, Yang, Fei, Gong, Quan, Kuczma, Michal, Kraj, Piotr, Gu, Weikuan, Ren, Bo-Xu, Wang, Cong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486856/
https://www.ncbi.nlm.nih.gov/pubmed/26035381
http://dx.doi.org/10.1242/dmm.018242