Beta-cell regeneration from vimentin(+)/MafB(+) cells after STZ-induced extreme beta-cell ablation

Loss of functional beta-cells is fundamental in both type 1 and type 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination of pre-existing beta cells by a single high-dose of streptozotocin (STZ), we demonstrated...

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Detalles Bibliográficos
Autores principales: Cheng, Yu, Kang, Hongjun, Shen, Jing, Hao, Haojie, Liu, Jiejie, Guo, Yelei, Mu, Yiming, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486952/
https://www.ncbi.nlm.nih.gov/pubmed/26129776
http://dx.doi.org/10.1038/srep11703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486952/
https://www.ncbi.nlm.nih.gov/pubmed/26129776
http://dx.doi.org/10.1038/srep11703

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