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Beta-cell regeneration from vimentin(+)/MafB(+) cells after STZ-induced extreme beta-cell ablation
Loss of functional beta-cells is fundamental in both type 1 and type 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination of pre-existing beta cells by a single high-dose of streptozotocin (STZ), we demonstrated...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486952/ https://www.ncbi.nlm.nih.gov/pubmed/26129776 http://dx.doi.org/10.1038/srep11703 |