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Heparin interacts with elongation factor 1α of Cryptosporidium parvum and inhibits invasion

Cryptosporidium parvum is an apicomplexan parasite that can cause serious watery diarrhea, cryptosporidiosis, in human and other mammals. C. parvum invades gastrointestinal epithelial cells, which have abundant glycosaminoglycans on their cell surface. However, little is known about the interaction...

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Detalles Bibliográficos
Autores principales: Inomata, Atsuko, Murakoshi, Fumi, Ishiwa, Akiko, Takano, Ryo, Takemae, Hitoshi, Sugi, Tatsuki, Cagayat Recuenco, Frances, Horimoto, Taisuke, Kato, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486996/
https://www.ncbi.nlm.nih.gov/pubmed/26129968
http://dx.doi.org/10.1038/srep11599