Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

Small RNAs play crucial roles in regulating gene expression during mammalian meiosis. To investigate the function of microRNAs (miRNAs) and small interfering RNAs (siRNAs) during meiosis in males, we generated germ-cell-specific conditional deletions of Dgcr8 and Dicer in mice. Analysis of spermatoc...

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Detalles Bibliográficos
Autores principales: Modzelewski, Andrew J., Hilz, Stephanie, Crate, Elizabeth A., Schweidenback, Caterina T. H., Fogarty, Elizabeth A., Grenier, Jennifer K., Freire, Raimundo, Cohen, Paula E., Grimson, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487015/
https://www.ncbi.nlm.nih.gov/pubmed/25934699
http://dx.doi.org/10.1242/jcs.167148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487015/
https://www.ncbi.nlm.nih.gov/pubmed/25934699
http://dx.doi.org/10.1242/jcs.167148

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