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Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations

We used multiple sets of simulations both at the atomistic and coarse-grained level of resolution to investigate interaction and binding of α-tochoperol transfer protein (α-TTP) to phosphatidylinositol phosphate lipids (PIPs). Our calculations indicate that enrichment of membranes with such lipids f...

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Detalles Bibliográficos
Autores principales: Lamprakis, Christos, Stocker, Achim, Cascella, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487086/
https://www.ncbi.nlm.nih.gov/pubmed/26191529
http://dx.doi.org/10.3389/fmolb.2015.00036