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Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations
We used multiple sets of simulations both at the atomistic and coarse-grained level of resolution to investigate interaction and binding of α-tochoperol transfer protein (α-TTP) to phosphatidylinositol phosphate lipids (PIPs). Our calculations indicate that enrichment of membranes with such lipids f...
Autores principales: | Lamprakis, Christos, Stocker, Achim, Cascella, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487086/ https://www.ncbi.nlm.nih.gov/pubmed/26191529 http://dx.doi.org/10.3389/fmolb.2015.00036 |
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