Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis

INTRODUCTION: Systemic sclerosis is an autoimmune disease characterized by inflammation and fibrosis of the skin and internal organs. We sought to assess the clinical and molecular effects associated with response to intravenous abatacept in patients with diffuse cutaneous systemic. METHODS: Adult d...

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Autores principales: Chakravarty, Eliza F., Martyanov, Viktor, Fiorentino, David, Wood, Tammara A., Haddon, David James, Jarrell, Justin Ansel, Utz, Paul J., Genovese, Mark C., Whitfield, Michael L., Chung, Lorinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487200/
https://www.ncbi.nlm.nih.gov/pubmed/26071192
http://dx.doi.org/10.1186/s13075-015-0669-3