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Function-Based Mutation-Resistant Synthetic Signaling Device Activated by HIV-1 Proteolysis
[Image: see text] The high mutation rate of the human immunodeficiency virus type 1 (HIV-1) virus is a major problem since it evades the function of antibodies and chemical inhibitors. Here, we demonstrate a viral detection strategy based on synthetic biology principles to detect a specific viral fu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487218/ https://www.ncbi.nlm.nih.gov/pubmed/25393958 http://dx.doi.org/10.1021/sb5002483 |