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Function-Based Mutation-Resistant Synthetic Signaling Device Activated by HIV-1 Proteolysis

[Image: see text] The high mutation rate of the human immunodeficiency virus type 1 (HIV-1) virus is a major problem since it evades the function of antibodies and chemical inhibitors. Here, we demonstrate a viral detection strategy based on synthetic biology principles to detect a specific viral fu...

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Detalles Bibliográficos
Autores principales: Majerle, Andreja, Gaber, Rok, Benčina, Mojca, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487218/
https://www.ncbi.nlm.nih.gov/pubmed/25393958
http://dx.doi.org/10.1021/sb5002483